Rami N. Hannoush joined the Early Discovery Biochemistry department at Genentech in 2006 after completing his postdoctoral fellowship at Harvard and his Ph.D. degree at McGill University. His current role includes leading interdisciplinary teams in lead discovery and research biology, with the overarching goal of developing therapeutics for the treatment of diseases with unmet medical needs. He has a deep and broad interest in science and translational research, and Genentech offers a unique opportunity to conduct groundbreaking science and at the same time translate our discoveries into the clinic.

This talk will describe our efforts in discovering and optimizing peptide-based scaffolds and will highlight some of the challenges and novel technologies for peptide lead identification and development. A few case studies will be presented, including the reprogramming of stem cells in the context of cellular regeneration.